THE LATEST TECHNOLOGY IN EARLY DETECTION AND HANDLING OF FUNGUS IN HOSPITALS: A LITERATURE REVIEW

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M Irhas Said

Abstract

Pathogenic fungi can cause serious infections in hospitals, especially in patients with weakened immune systems. Early detection and prompt management are crucial to reducing morbidity and mortality. The latest technology in fungal diagnosis and therapy holds great potential for improving clinical outcomes. This research is a literature review that examines various latest technologies used in the early detection and management of fungal infections in hospitals. Relevant articles from various medical and technology databases are selected and analysed to identify the latest trends in this field. The research findings indicate that various technologies, such as PCR-based detection, biosensor sensors, and advanced imaging technologies like MRI and CT scans, have demonstrated better capabilities in early fungal detection. Moreover, AI and machine learning-based approaches have shown great potential in optimising treatment and reducing diagnosis time. The latest technology in the detection and management of fungal infections in hospitals has shown significant progress. Further implementation of these technologies can accelerate diagnosis, improve treatment efficiency, and reduce the risk of complications. Further research is needed to evaluate the long-term effectiveness of this technology in clinical practice.

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References

Afanou, A. K., Straumfors, A., & Eduard, W. (2019). Fungal aerosol composition in moldy basements. Indoor Air, 29(5), 780–790. https://doi.org/10.1111/ina.12567

Calley, J. L., & Warris, A. (2017). Recognition and diagnosis of invasive fungal infections in neonates. Journal of Infection, 74, S108–S113. https://doi.org/10.1016/S0163-4453(17)30200-1

Dashti, M., Dargahi, A., Sadeghi, H., Vosoughi, M., & Mokhtari, S. A. (2022). Removal of Microorganisms by UVC Radiation From the Air of Hospital. Avicenna Journal of Environmental Health Engineering, 9(1), 35–44. https://doi.org/10.34172/ajehe.2022.05

Domínguez-Morueco, N., Moreno, H., Barreno, E., & Catalá, M. (2014). Preliminary assessment of terrestrial microalgae isolated from lichens as testing species for environmental monitoring: Lichen phycobionts present high sensitivity to environmental micropollutants. Ecotoxicology and Environmental Safety, 99, 35–44. https://doi.org/10.1016/j.ecoenv.2013.10.007

Dou, J. P., Li, H., Pang, X. L., Zhang, C. N., Yang, T. H., & Jin, X. M. (2019). Research progress of quantum memory. Wuli Xuebao/Acta Physica Sinica, 68(3). https://doi.org/10.7498/aps.68.20190039

Fan, L., Wang, J., Yang, Y., Yang, W., Zhu, Y., Zhang, Y., Li, L., Li, X., Yan, X., Yao, X., Wang, L., & Wang, X. (2021). Residential airborne culturable fungi under general living scenario: On-site investigation in 12 typical cities, China. Environment International, 155. https://doi.org/10.1016/j.envint.2021.106669

Fedor, L., Nakládalová, M., Štěpánek, L., Holý, O., & Matoušková, I. (2022). Effectiveness of Anti-Epidemic Measures on Ensuring Indoor Air Quality of Cleanrooms in a Tertiary Care Hospital. Central European Journal of Public Health, 30(2), 74–78. https://doi.org/10.21101/cejph.a7060

Hashimoto, K., & Kawakami, Y. (2018). Effectiveness of airborne fungi removal by using a HEPA air purifier fan in houses. Biocontrol Science, 23(4), 215–221. https://doi.org/10.4265/bio.23.215

Hemati, S., Mobini, G. R., Heidari, M., Rahmani, F., Soleymani Babadi, A., Farhadkhani, M., Nourmoradi, H., Raeisi, A., Ahmadi, A., Khodabakhshi, A., Sadeghi, M., Bagheri, M., Validi, M., Taghipour, S., & Mohammadi-Moghadam, F. (2021). Simultaneous monitoring of SARS-CoV-2, bacteria, and fungi in indoor air of hospital: a study on Hajar Hospital in Shahrekord, Iran. Environmental Science and Pollution Research, 28(32), 43792–43802. https://doi.org/10.1007/s11356-021-13628-9

Hosein, I., Madeloso, R., Nagaratnam, W., Villamaria, F., Stock, E., & Jinadatha, C. (2016). Evaluation of a pulsed xenon ultraviolet light device for isolation room disinfection in a United Kingdom hospital. American Journal of Infection Control, 44(9), e157–e161. https://doi.org/10.1016/j.ajic.2016.01.044

Kanamori, H., Rutala, W. A., Sickbert-Bennett, E. E., & Weber, D. J. (2015). Review of Fungal Outbreaks and Infection Prevention in Healthcare Settings during Construction and Renovation. Clinical Infectious Diseases, 61(3), 433–444. https://doi.org/10.1093/cid/civ297

Kozel, T. R., & Wickes, B. (2014). Fungal diagnostics. Cold Spring Harbor Perspectives in Medicine, 4(4). https://doi.org/10.1101/cshperspect.a019299

La Milia, D. I., Vincenti, S., Fiori, B., Pattavina, F., Torelli, R., Barbara, A., Wachocka, M., Moscato, U., Sica, S., Amato, V., Ricciardi, W., & Laurenti, P. (2019). Monitoring of particle environmental pollution and fungal isolations during hospital building-work activities in a hematology ward. Mediterranean Journal of Hematology and Infectious Diseases, 11(1), 1–9. https://doi.org/10.4084/MJHID.2019.062

Lauruschkat, C. D., Etter, S., Schnack, E., Ebel, F., Schäuble, S., Page, L., Rümens, D., Dragan, M., Schlegel, N., Panagiotou, G., Kniemeyer, O., Brakhage, A. A., Einsele, H., Wurster, S., & Loeffler, J. (2021). Chronic occupational mold exposure drives expansion of aspergillus-reactive type 1 and type 2 t-helper cell responses. Journal of Fungi, 7(9), 1–15. https://doi.org/10.3390/jof7090698

Lee, J. K., & Jeong, H. W. (2020). Rapid expansion of temporary, reliable airborne-infection isolation rooms with negative air machines for critical COVID-19 patients. American Journal of Infection Control, 48(7), 822–824. https://doi.org/10.1016/j.ajic.2020.04.022

Park, J. H., Ryu, S. H., Lee, J. Y., Kim, H. J., Kwak, S. H., Jung, J., Lee, J., Sung, H., & Kim, S. H. (2019). Airborne fungal spores and invasive aspergillosis in hematologic units in a tertiary hospital during construction: A prospective cohort study. Antimicrobial Resistance and Infection Control, 8(1), 1–8. https://doi.org/10.1186/s13756-019-0543-1

Santos, T. dos, & de Castro, L. F. (2021). Evaluation of a portable Ultraviolet C (UV-C) device for hospital surface decontamination. Photodiagnosis and Photodynamic Therapy, 33(October 2020), 102161. https://doi.org/10.1016/j.pdpdt.2020.102161

Savory, E., Sabarinathan, J., Sauer, A., & Scott, J. A. (2012). An optoelectronic sensor for the monitoring of mould growth in concealed spaces. Building and Environment, 49(1), 9–16. https://doi.org/10.1016/j.buildenv.2011.09.023

Shabbir, J., Anis, A., Ul Hasan, S. M. ul H., Najmi, N., Anis, M. M., Zehra, T., & Saghir, W. (2023). Evaluation of Presence and Amount of Moisture in Dry Air of Three Way Syringes in Dental Teaching Hospitals and Private Clinics: A Cross-Sectional Study. Journal of the Pakistan Dental Association, 31(04), 176–181. https://doi.org/10.25301/jpda.314.176

Somogyvari, F., Horvath, A., Serly, J., Majoros, H., Vagvolgyi, C., & Peto, Z. (2012). Detection of invasive fungal pathogens by real-time PCR and high-resolution melting analysis. In Vivo, 26(6), 979–983.

Tršan, M., Seme, K., & Srčič, S. (2019). The environmental monitoring in hospital pharmacy cleanroom and microbiota catalogue preparation. Saudi Pharmaceutical Journal, 27(4), 455–462. https://doi.org/10.1016/j.jsps.2019.01.007

Viegas, C., Viegas, S., Gomes, A. Q., Täubel, M., & Sabino, R. (2017). Exposure to microbiological agents in indoor and occupational environments. Exposure to Microbiological Agents in Indoor and Occupational Environments, 1–415. https://doi.org/10.1007/978-3-319-61688-9

Wu, H., Ng, T. W., Wong, J. W. C., & Lai, K. M. (2018). Environmental sustainability and mold hygiene in buildings. International Journal of Environmental Research and Public Health, 15(4). https://doi.org/10.3390/ijerph15040681