Patient and Healthcare Provider Experiences with Technology-Based Medications in Cancer Therapy

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Doby Indrawan
Dyah Pramesti Gayuh Utami Asih Lestari

Abstract

The integration of technology in healthcare, particularly in cancer treatment, has led to significant advancements in treatment efficacy. However, the subjective experiences of patients and healthcare professionals regarding technology-based medications remain underexplored. While previous studies focus on clinical outcomes, little is known about how these technologies are perceived on an emotional and relational level. This study addresses this gap by adopting a phenomenological approach to examine the lived experiences of both patients and healthcare professionals using technology-based medications in cancer therapy. Data were collected through in-depth, semi-structured interviews with 12 participants, including 6 patients and 6 healthcare providers. Thematic analysis revealed three major themes: (1) enhanced therapeutic precision and monitoring, (2) emotional ambivalence toward technology use, and (3) perceived shifts in patient–provider relationships. Ten out of twelve participants emphasized improved treatment accuracy and real-time monitoring as key benefits, while eight participants reported feelings of emotional distance or reduced interpersonal interaction during technology-mediated care. Additionally, five healthcare providers expressed concern that increased reliance on digital systems limited opportunities for empathetic communication. These findings highlight the need for a balanced approach that integrates technology while maintaining human aspects of patient care. The results contribute to a deeper understanding of how technology affects the emotional and relational dynamics in healthcare, providing a foundation for future research aimed at improving the integration of technological advancements in patient-centered care.

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Arbyn, M., Weiderpass, E., Bruni, L., de Sanjosé, S., Saraiya, M., Ferlay, J., & Bray, F. (2020). Estimates of incidence and mortality of cervical cancer in 2018: A worldwide analysis. The Lancet Global Health, 8(2), e191–e203. Scopus. https://doi.org/10.1016/S2214-109X(19)30482-6

Bailey, S. C., Griffith, J. W., Vuyyuru, C., Batio, S., Velazquez, E., Carpenter, D. M., Davis, T. C., Parker, R. M., Taddeo, M., & Wolf, M. S. (2023). Development and Validation of the HL6: A Brief, Technology-Based Remote Measure of Health Literacy. Journal of General Internal Medicine, 38(2), 421–427. Scopus. https://doi.org/10.1007/s11606-022-07739-3

Berdeja, J. G., Madduri, D., Usmani, S. Z., Jakubowiak, A., Agha, M., Cohen, A. D., Stewart, A. K., Hari, P., Htut, M., Lesokhin, A., Deol, A., Munshi, N. C., O’Donnell, E., Avigan, D., Singh, I., Zudaire, E., Yeh, T.-M., Allred, A. J., Olyslager, Y., … Jagannath, S. (2021). Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): A phase 1b/2 open-label study. The Lancet, 398(10297), 314–324. Scopus. https://doi.org/10.1016/S0140-6736(21)00933-8

Bergman, B. G., Wu, W., Marsch, L. A., Crosier, B. S., DeLise, T. C., & Hassanpour, S. (2020). Associations between substance use and instagram participation to inform social network-based screening models: Multimodal cross-sectional study. Journal of Medical Internet Research, 22(9). Scopus. https://doi.org/10.2196/21916

Bhidayasiri, R., Lean, P. L., & Chaudhuri, K. R. (2025). Defining ‘OFF’ time in device-aided therapy criteria for Parkinson’s disease: Gaps and opportunities. Parkinsonism and Related Disorders, 139. Scopus. https://doi.org/10.1016/j.parkreldis.2025.107894

Chalabi, M., Fanchi, L. F., Dijkstra, K. K., van den Berg, J. G., Aalbers, A. G., Sikorska, K., Lopez-Yurda, M., Grootscholten, C., Beets, G. L., Snæbjörnsson, P., Maas, M., Mertz, M., Veninga, V., Bounova, G., Broeks, A., Beets-Tan, R. G., de Wijkerslooth, T. R., van Lent, A. U., Marsman, H. A., … Haanen, J. B. (2020). Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers. Nature Medicine, 26(4), 566–576. Scopus. https://doi.org/10.1038/s41591-020-0805-8

Davies, E. H., Fieggen, K., Wilmshurst, J., Anyanwu, O., Burman, R. J., & Komarzynski, S. (2021). Demonstrating the feasibility of digital health to support pediatric patients in South Africa. Epilepsia Open, 6(4), 653–662. Scopus. https://doi.org/10.1002/epi4.12527

Davis, A. K., Barrett, F. S., May, D. G., Cosimano, M. P., Sepeda, N. D., Johnson, M. W., Finan, P. H., & Griffiths, R. R. (2021). Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry, 78(5), 481–489. Scopus. https://doi.org/10.1001/jamapsychiatry.2020.3285

Fogarty, H., Gaul, A., Syed, S., Aleksejenko, N., Geoghegan, R., Conroy, H., Crampton, E., Ngwenya, N., Tuohy, E., & Mcmahon, C. (2022). Adherence to hydroxyurea, health-related quality of life domains and attitudes towards a smartphone app among Irish adolescents and young adults with sickle cell disease. Irish Journal of Medical Science, 191(2), 809–816. Scopus. https://doi.org/10.1007/s11845-021-02588-1

Gaspar, F., Lutters, M., Beeler, P. E., Lang, P. O., Burnand, B., Rinaldi, F., Lovis, C., Csajka, C., & LE POGAM, M. A. (2022). Automatic Detection of Adverse Drug Events in Geriatric Care: Study Proposal. JMIR Research Protocols, 11(11). Scopus. https://doi.org/10.2196/40456

Goulding, E. H., Dopke, C. A., Michaels, T., Martin, C. R., Khiani, M. A., Garborg, C., Karr, C., & Begale, M. (2021). A Smartphone-Based Self-management Intervention for Individuals with Bipolar Disorder (LiveWell): Protocol Development for an Expert System to Provide Adaptive User Feedback. JMIR Formative Research, 5(12). Scopus. https://doi.org/10.2196/32932

Hashiguchi, Y., Muro, K., Saito, Y., Ito, Y., Ajioka, Y., Hamaguchi, T., Hasegawa, K., Hotta, K., Ishida, H., Ishiguro, M., Ishihara, S., Kanemitsu, Y., Kinugasa, Y., Murofushi, K., Eguchi Nakajima, T. E., Oka, S., Tanaka, T., Taniguchi, H., Tsuji, A., … Sugihara, K. (2020). Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer. International Journal of Clinical Oncology, 25(1), 1–42. Scopus. https://doi.org/10.1007/s10147-019-01485-z

Li, L., Zhang, W., Hu, Y., Tong, X., Zheng, S., Juntao, J., Kong, Y., Ren, L., Wei, Q., Mei, H., Hu, C., Tao, C., Yang, R., Wang, J., Yu, Y., Guo, Y., Wu, X., Xu, Z., Zeng, L., … Liu, Z. (2020). Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients with Severe and Life-threatening COVID-19: A Randomized Clinical Trial. JAMA, 324(5), 460–470. Scopus. https://doi.org/10.1001/jama.2020.10044

Li, Y., Gong, Y., Zheng, B., Fan, F., Yi, T., Zheng, Y., He, P., Fang, J., Jia, J., Zhu, Q., Jiang, J., & Huo, Y. (2022). Effects on Adherence to a Mobile App–Based Self-management Digital Therapeutics Among Patients With Coronary Heart Disease: Pilot Randomized Controlled Trial. JMIR mHealth and uHealth, 10(2). Scopus. https://doi.org/10.2196/32251

Lyon, A. R., Fernández, T., Couch, L. S., Asteggiano, R., Aznar, M. C., Bergler-Klei, J., Boriani, G., Cardinale, D., Córdoba-Mascuñano, R., Cosyns, B., Cutter, D. J., de Azambuja, E., De Boer, R. A., Dent, S. F., Farmakis, D., Gevaert, S. A., Gorog, D. A., Herrmann, J., Lenihan, D., … Smyth, Y. (2022). 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS). European Heart Journal, 43(41), 4229–4361. Scopus. https://doi.org/10.1093/eurheartj/ehac244

Mammen, J. R., Java, J. J., Halterman, J., Berliant, M. N., Crowley, A., Frey, S. M., Reznik, M., Feldman, J. M., Schoonmaker, J. D., & Arcoleo, K. (2021). Development and preliminary results of an Electronic Medical Record (EMR)-integrated smartphone telemedicine program to deliver asthma care remotely. Journal of Telemedicine and Telecare, 27(4), 217–230. Scopus. https://doi.org/10.1177/1357633X19870025

Morales-Pillado, C., Fernandez-Castilla, B., Sánchez-Gutiérrez, T., Gonzalez-Fraile, E., Barbeito Resa, S., & Calvo Calvo, A. (2023). Efficacy of technology-based interventions in psychosis: A systematic review and network meta-analysis. Psychological Medicine, 53(13), 6304–6315. Scopus. https://doi.org/10.1017/S0033291722003610

Mukhlis, L. (2025a). A Phenomenological Study of Personal Spiritual Experiences in Navigating Religious Pluralism within Interfaith Communities. Irfana: Journal of Religious Studies, 1(6), 212–220.

Mukhlis, L. (2025b). Spiritual Grounds for Economic Growth: A Qualitative Exploration of Rural Indonesian Women’s Transformative Journeys Through Mosque-Led Empowerment Programs. Servina: Jurnal Pengabdian Kepada Masyarakat, 1(8), 289–298.

Mukhlis, L., & Abdullah, M. N. (2025). Hukum Keluarga Islam di Indonesia (1st ed.). Mukhlisina Revolution Center.

Mukhlis, L., Arifin, T., Ridwan, A. H., & Zulbaidah. (2024). Integrating Artificial Intelligenceand Maqāṣid al-Syarī‘ah: Revolutionizing Indonesia’s Sharia Online Trading System. Computer Fraud and Security, 2024(11), 301–309. https://doi.org/10.52710/cfs.238

Mukhlis, L., Arifin, T., Ridwan, A. H., & Zulbaidah. (2025). Reorientation of Sharia Stock Regulations: Integrating Taṣarrufāt al-Rasūl and Maqāṣid al-Sharī‘ah for Justice and Sustainability. Journal of Information Systems Engineering and Management, 10(10s), 58–66. https://doi.org/10.52783/jisem.v10i10s.1341

Mukhlis, L., Arifin, T., Ridwan, A. H., Zulbaidah, Rosadi, A., & Solehudin, E. (2025). Reformulation of Islamic Stock Law: The Application of Taṣarrufāt al-Rasūl and Maqāṣid al-Syarī‘ahto Develop a Dynamic and Sustainable Islamic Capital Market in Indonesia. Journal of Posthumanism, 5(3), 1–13. https://doi.org/10.63332/joph.v5i3.913

Mukhlis, L., Janwari, Y., & Syafe`i, R. (2023). INDONESIA STOCK EXCHANGE: THEORETICAL AND PHILOSOPHICAL ANALYSIS OF MUDHARABAH AND MUSYARAKAH CONTRACTS. Yurisprudentia: Jurnal Hukum Ekonomi, 9(2), 243–264. https://doi.org/10.24952/yurisprudentia.v9i2.8466

Mukhlis, L., Maryam, S., & Sormin, S. A. (2023). Model Pembelajaran Living History Berbasis PjBL Untuk Meningkatkan Keterampilan Histografi Mahasiswa. Jurnal Educatio FKIP UNMA, 9(4), 1800–1809. https://doi.org/10.31949/educatio.v9i4.5595

Mukhlis, L., & Saidah, Y. (2025). Dynamics of Nature-Based learning in Developing Children’s Motoricic Skills: Teacher and Parent Perspectives. HUMANISMA: Journal of Gender Studies, 9(1), 64–79. http://dx.doi.org/10.30983/humanisme.v4i2.9366

Mukhlis, L., Suradi, Janwari, Y., & Syafe`i, R. (2023). Sosialisasi Saham Syariah sebagai Instrumen Pengembangan Ekonomi Masyarakat di Badan Kontak Majelis Taklim (BKMT) Kabupaten Mandailing Natal. Jurnal Pengabdian Multidisiplin, 3(2), 2–9. https://doi.org/10.51214/japamul.v3i2.604

Murali, K. M., & Lonergan, M. (2020). Breaking the adherence barriers: Strategies to improve treatment adherence in dialysis patients. Seminars in Dialysis, 33(6), 475–485. Scopus. https://doi.org/10.1111/sdi.12925

Murphy, J., McSharry, J., Hynes, L., & Molloy, G. J. (2021). A smartphone app to support adherence to inhaled corticosteroids in young adults with asthma: Multi-methods feasibility study. JMIR Formative Research, 5(9). Scopus. https://doi.org/10.2196/28784

Ortiz Arduán, A., Portolés-Pérez, J., Pino-Pino, M. D., Barea, J., López, M., De Sequera, P., Quiroga Gili, B., Echarri, R., Prieto-Velasco, M., Díaz, R., Gómez Marqués, G., Sánchez Pérez, P., Torregrosa, V., & Rodríguez-Portillo, M. (2023). Clinical Characteristics and Management of Patients with Secondary Hyperparathyroidism Undergoing Hemodialysis: A Feasibility Analysis of Electronic Health Records Using Natural Language Processing. Kidney Diseases, 9(3), 187–196. Scopus. https://doi.org/10.1159/000528784

Palma, D. A., Olson, R., Harrow, S., Gaede, S., Louie, A. V., Haasbeek, C., Mulroy, L., Lock, M., Rodrigues, G. B., Yaremko, B. P., Schellenberg, D., Ahmad, B., Senthi, S., Swaminath, A., Kopek, N., Liu, M., Moore, K., Currie, S., Schlijper, R., … Senan, S. (2020). Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: Long-term results of the SABR-COMET Phase II randomized trial. Journal of Clinical Oncology, 38(25), 2830–2838. Scopus. https://doi.org/10.1200/JCO.20.00818

Rasschaert, M., Vulsteke, C., de Keersmaeker, S., Vandenborne, K., Dias, S., Verschaeve, V., Vuylsteke, P., Brussel, I. V., Ravelingien, J., Dam, P. V., Segelov, E., & Peeters, M. (2021). AMTRA: a multicentered experience of a web-based monitoring and tailored toxicity management system for cancer patients. Supportive Care in Cancer, 29(2), 859–867. Scopus. https://doi.org/10.1007/s00520-020-05550-6

Sartor, O., De Bono, J., Chi, K. N., Fizazi, K., Herrmann, K., Rahbar, K., Tagawa, S. T., Nordquist, L. T., Vaishampayan, N., El-Haddad, G., Park, C. H., Beer, T. M., Armour, A., Perez-Contreras, W. J., de Silvio, M., Kpamegan, E., Gericke, G., Messmann, R. A., Morris, M. J., & Krause, B. J. (2021). Lutetium-177-PSMA-617 for metastatic castration-resistant prostate cancer. New England Journal of Medicine, 385(12), 1091–1103. Scopus. https://doi.org/10.1056/NEJMoa2107322

Schwartz, J., & Ballard, D. H. (2022). Feasibility of Customized Pillboxes to Enhance Medication Adherence: A Randomized Controlled Trial. Archives of Physical Medicine and Rehabilitation, 103(12), 2288–2295. Scopus. https://doi.org/10.1016/j.apmr.2022.03.018

Singal, A. G., Llovet, J. M., Yarchoan, M., Mehta, N., Heimbach, J. K., Dawson, L. A., Jou, J. H., Kulik, L. M., Agopian, V. G., Marrero, J. A., Mendiratta-Lala, M., Brown, D. B., Rilling, W. S., Goyal, L., Wei, A. C., & Taddei, T. H. (2023). AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma. Hepatology, 78(6), 1922–1965. Scopus. https://doi.org/10.1097/HEP.0000000000000466

Still, C. H., Margevicius, S. P., Harwell, C., Huang, M.-C., Martin, L., Dang, P. B., & Wright, J. T. (2020). A community and technology-based approach for hypertension self-management (Coachman) to improve blood pressure control in african americans: Results from a pilot study. Patient Preference and Adherence, 14, 2301–2313. Scopus. https://doi.org/10.2147/PPA.S283086

Still, C. H., Margevicius, S. P., Wright, J. T., Ruksakulpiwat, S., & Moore, S. M. (2021). A Pilot Study Evaluating the Effects of a Technology-Based and Positive Psychological Training Intervention on Blood Pressure in African Americans With Hypertension. Journal of Primary Care and Community Health, 12. Scopus. https://doi.org/10.1177/21501327211056186

Stockman, J. K., Anderson, K. M., DeSoto, A. F., Campbell, D. M., Tsuyuki, K., & Horvath, K. J. (2023). A Trauma-Informed HIV Intervention (LinkPositively) to Improve HIV Care Among Black Women Affected by Interpersonal Violence: Protocol for a Pilot Randomized Controlled Trial. JMIR Research Protocols, 12. Scopus. https://doi.org/10.2196/46325

Toscos, T., Coupe, A., Wagner, S., Ahmed, R., Roebuck, A., Flanagan, M., Drouin, M., & Mirro, M. (2020). Engaging Patients in Atrial Fibrillation Management via Digital Health Technology: The Impact of Tailored Messaging. Journal of Innovations in Cardiac Rhythm Management, 11(8), 4209–4217. Scopus. https://doi.org/10.19102/ICRM.2020.110802

Wang, M., Munoz, J., Goy, A., Locke, F. L., Jacobson, C. A., Hill, B. T., Timmerman, J. M., Holmes, H., Jaglowski, S., Flinn, I. W., McSweeney, P. A., Miklos, D. B., Pagel, J. M., Kersten, M.-J., Milpied, N., Fung, H., Topp, M. S., Houot, R., Beitinjaneh, A., … Reagan, P. M. (2020). KTE-X19 CAR T-Cell therapy in relapsed or refractory mantle-cell lymphoma. New England Journal of Medicine, 382(14), 1331–1342. Scopus. https://doi.org/10.1056/NEJMoa1914347