Exploring the Meaning of Hope and Uncertainty among Patients Undergoing Experimental Regenerative Therapy in Indonesia: A Phenomenological Study
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Abstract
Background: Regenerative therapy has emerged as a cutting-edge biomedical innovation aimed at treating chronic and degenerative diseases through interventions such as stem cell and molecular-based treatments. While its clinical promise is significant, little is known about how patients experience hope and uncertainty during such experimental treatments. Previous research has focused mainly on outcomes, leaving a gap in understanding the subjective experiences of patients.
Methods: This study applied a descriptive phenomenological design to explore how individuals with chronic illnesses interpret hope and uncertainty in the context of regenerative therapy. In-depth semi-structured interviews were conducted with eight participants from specialized clinics in Indonesia. Thematic analysis was used to identify core experiential themes.
Results: Four key themes emerged: hope as a vital force, uncertainty as a psychological burden, the role of healthcare relationships in shaping perception, and therapy as a path to existential meaning.
Conclusion: These findings show that hope and uncertainty are shaped by patients' cultural, relational, and spiritual contexts. Rather than abstract emotions, they are experienced as deeply embodied phenomena. This study contributes to a richer understanding of patient perspectives in experimental medical settings and highlights the need for empathetic communication and culturally sensitive care. The insights may guide future interdisciplinary research and patient-centered practices in regenerative medicine.
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References
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