Exploration of the Experience of Using Herbal Medicine in the Treatment of Chronic Diseases: A Phenomenological Approach to Patients' Perceptions of Effectiveness, Safety, and the Mechanisms of Action of Natural Compounds
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Abstract
The use of herbal medicines as an alternative or complementary treatment for chronic diseases has gained significant popularity, yet the mechanisms, effectiveness, and safety of these treatments remain insufficiently understood. While existing studies primarily focus on clinical outcomes, little is known about patients' subjective experiences and perceptions of herbal remedies in managing chronic conditions. This research aims to explore these experiences using a phenomenological approach, addressing the gap in understanding the lived experiences of patients who use herbal medicines for chronic disease treatment. In-depth interviews were conducted with 15-20 patients who had used herbal medicines for at least six months, and data were analyzed thematically. The findings reveal that patients generally perceive herbal remedies as effective but are uncertain about their mechanisms and safety, with cultural beliefs and lack of medical guidance influencing their decisions. These findings offer practical implications for healthcare providers by emphasizing the importance of integrating patient education about the safe use of herbal medicines into routine care. Healthcare professionals can play a critical role in guiding patients to make informed decisions and minimize potential risks. Additionally, this research underscores the necessity of developing standardized frameworks for evaluating the efficacy and safety of herbal treatments.
This study also contributes to the existing literature by filling a significant gap in understanding patients' lived experiences with herbal medicines. It expands the discourse on complementary therapies by providing evidence-based insights into patient perceptions and their decision-making processes. By highlighting the interplay between cultural beliefs, patient education, and medical guidance, this research serves as a foundation for future studies aimed at bridging the gap between traditional and modern medical practices. Overall, the findings suggest that future research should prioritize collaboration between traditional medicine practitioners and modern healthcare professionals, as well as investigate strategies to incorporate herbal therapies safely and effectively into holistic chronic disease management.
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References
Altenbernd, F., Schwarz, L., Lipowicz, B., & Vissiennon, C. (2022). Myrrh and chamomile flower extract inhibit mediator release from IgE-stimulated mast-cell-like RBL-2H3 cells. Plants, 11(24), Article 3422. https://doi.org/10.3390/plants11243422
Badary, O. A., Hamza, M. S., & Tikamdas, R. (2021). Thymoquinone: A promising natural compound with potential benefits for COVID-19 prevention and cure. Drug Design, Development and Therapy, 15, 1819–1833. https://doi.org/10.2147/DDDT.S308863
Borghi, S. M., Zaninelli, T. H., Carra, J. B., Heintz, O. K., Baracat, M. M., Georgetti, S. R., Vicentini, F. T. M. C., Verri, W. A., & Casagrande, R. (2023). Therapeutic potential of controlled delivery systems in asthma: Preclinical development of flavonoid-based treatments. Pharmaceutics, 15(1), Article 1. https://doi.org/10.3390/pharmaceutics15010001
Ciulla, M., Marinelli, L., Cacciatore, I., & Di Stefano, A. (2019). Role of dietary supplements in the management of Parkinson’s disease. Biomolecules, 9(7), Article 271. https://doi.org/10.3390/biom9070271
D’amico, R., Trovato Salinaro, A., Cordaro, M., Fusco, R., Impellizzeri, D., Interdonato, L., Scuto, M., Ontario, M. L., Crea, R., Siracusa, R., Cuzzocrea, S., Di Paola, R., & Calabrese, V. (2021). Hidrox® and chronic cystitis: Biochemical evaluation of inflammation, oxidative stress, and pain. Antioxidants, 10(7), Article 1046. https://doi.org/10.3390/antiox10071046
Feldo, M., Wójciak-Kosior, M., Sowa, I., Kocki, J., Bogucki, J., Zubilewicz, T., Kȩsik, J., & Bogucka-Kocka, A. (2019). Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis. Molecules, 24(18), Article 3316. https://doi.org/10.3390/molecules24183316
Ghosh, J., Choudhury, S. R., & Koner, S. (2024). Role of nutraceuticals in managing osteomyelitis. In Nutraceuticals and Bone Health (pp. 223–291). Apple Academic Press. https://doi.org/10.1201/9781003415084-13
Giovinazzo, G., Gerardi, C., Uberti-Foppa, C., & Lopalco, L. (2020). Can natural polyphenols help in reducing cytokine storm in COVID-19 patients? Molecules, 25(24), Article 5888. https://doi.org/10.3390/MOLECULES25245888
James, A., Gunasekaran, N., Krishnan, R., Arunachalam, P., & Mahalingam, R. (2022). Anti-fibrotic activity of licorice extract in comparison with colchicine on areca nut-induced fibroblasts: An in vitro study. Journal of Oral and Maxillofacial Pathology, 26(2), 173–178. https://doi.org/10.4103/jomfp.jomfp_110_21
Khader, B. M., Abu-Elsaoud, A. M., Darwish, A. M. G., & Abdel-Azeem, A. M. (2023). Endophytic fungi hosted by anti-diabetic medicinal plants as a source of α-Amylase and α-Glucosidase inhibitors. Microbial Biosystems, 8(2), 44–56. https://doi.org/10.21608/mb.2023.338902
Kim, G.-H., Kan, S.-Y., Kang, H., Lee, S., Ko, H. M., Kim, J. H., & Lim, J.-H. (2019). Ursolic acid suppresses cholesterol biosynthesis and exerts anti-cancer effects in hepatocellular carcinoma cells. International Journal of Molecular Sciences, 20(19), Article 4767. https://doi.org/10.3390/ijms20194767
Liu, P., Wang, F., Song, Y., Wang, M., & Zhang, X. (2022). Current situation and progress of drugs for reducing intraocular pressure. Therapeutic Advances in Chronic Disease, 13, Article 20406223221140392. https://doi.org/10.1177/20406223221140392Lombardi, V. R. M., Carrera, I., Corzo, L., & Cacabelos, R. (2019). Role of bioactive lipofishins in prevention of inflammation and colon cancer. Seminars in Cancer Biology, 56, 175–184. Scopus. https://doi.org/10.1016/j.semcancer.2017.11.012
Mahdavi, A., Bagherniya, M., Mirenayat, M. S., Atkin, S. L., & Sahebkar, A. (2021). Medicinal Plants and Phytochemicals Regulating Insulin Resistance and Glucose Homeostasis in Type 2 Diabetic Patients: A Clinical Review. Dalam 33861444, Advances in Experimental Medicine and Biology (Vol. 1308, hlm. 161–183). Springer; Scopus. https://doi.org/10.1007/978-3-030-64872-5_13
Martins, D. O. S., Santos, I. D. A., De Oliveira, D. M., Grosche, V. R., & Jardim, A. C. G. (2020). Antivirals against chikungunya virus: Is the solution in nature? Viruses, 12(3). Scopus. https://doi.org/10.3390/v12030272
Santana, M. S., Lopes, R., Peron, I. H., Cruz, C. R., Gaspar, A. M. M., & Costa, P. I. (2021). Natural bioactive compounds as adjuvant therapy for hepatitis c infection. Current Nutrition and Food Science, 17(5), 458–469. Scopus. https://doi.org/10.2174/1573401316999201009152726
Santos, J. D., Vitorino, I., De La Cruz, M., Díaz, C., Cautain, B., Annang, F., Pérez-Moreno, G., Martinez, I. G., Tormo, J. R., Martín, J. M., Urbatzka, R., Vicente, F. M., & Lage, O. M. (2019). Bioactivities and extract dereplication of actinomycetales isolated from marine sponges. Frontiers in Microbiology, 10(APR). Scopus. https://doi.org/10.3389/fmicb.2019.00727
Tanase, D. M., Gosav, E. M., Anton, M. I., Floria, M., Seritean Isac, P. N., Hurjui, L. L., Tarniceriu, C. C., Costea, C. F., Ciocoiu, M., & Rezus, C. (2022). Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives. Biomolecules, 12(9). Scopus. https://doi.org/10.3390/biom12091227